Company
(Symbol)#*

Date filed

Shares/Units (M)

Price

Shares out

Lead, other underwriters

Gross (US$M)

AC Immune SA (Lausanne, Switzerland; ACIU)

6/2/16

N/A

N/A

N/A

Credit Suisse; Jefferies; Leerink Partners

$50.00

Adalta Ltd. (Melbourne, Australia; ASX)1

7/12/16

N/A

N/A

N/A

N/A

$7.55

Advanced Inhalation Therapies Ltd. (Tel Aviv, Israel; AITP)2

8/27/15

0.675U

$15

2.3

Joseph Gunnar

$10.125

Anaptysbio Inc. (San Diego; ANAB)

9/9/15

N/A

N/A

N/A

Credit Suisse; Stifel; JMP Securities; Wedbush Securities

$86.25

Anterios Inc. (New York; ANTE)

4/2/15

3.9S

$12-$14

13.5

Stifel (co-lead); RBC Capital Markets (co-lead); JMP Securities; Needham & Co.

$50.7

Azurrx Biopharma Inc. (Brooklyn, N.Y.; AZRX)

7/15/16

2.14S

$6-$8

N/A

Wallachbeth Capital; Network 1 Financial Securities

$15.00

Biolight Life Sciences Ltd. (Tel Aviv, Israel; BOLT)3

2/10/16

1.848S and W for 1.848S

N/A

4.45

Feltl and Co.; Rodman & Renshaw

$10.00

Cancer Prevention Pharmaceuticals Inc. (Tucson, Ariz.; NYSE:CPP)

12/24/15

1.92S

$12-$14

7.42

Aegis Capital; Maxim Group

$24.96

Gan & Lee Pharmaceuticals Ltd. (China)4

6/15/16

N/A

N/A

N/A

N/A

$227.00

Gemphire Therapeutics Inc. (Northville, Mich.; GEMP)

4/18/16

3.8S

$11-$13

N/A

Jefferies; Cowen and Co.; Canaccord Genuity; Roth Capital Partners

$45.60

Lumena Pharmaceuticals Inc. (San Diego; LIVR)

4/2/14

N/A

N/A

N/A

Citigroup (co-lead); Cowen and Co. (co-lead); Leerink Partners (co-lead)

$75.00

Mapi-Pharma Ltd. (Ness Ziona; MAPI)

1/26/16

3.125S

$15-$17

11.76

JMP Securities; FBR; Maxim Group

$50

Motif Bio plc (London and New York; MTFB)

7/14/16

28S

$12.42

N/A

Suntrust Robinson Humphrey; Ladenburg Thalmann

$35.00

Nant Health LLC (Culver City, Calif.; NH)

5/25/16

6.5S

$12.50-$15.50

N/A

N/A

$91.00

Noxopharm Ltd. (Sydney; ASX)5

6/27/16

30S

$0.20

N/A

N/A

$4.40

Protagonist Therapeutics Inc. (Milpitas, Calif.; PTGX)

7/13/16

5.8S

$11-$13

N/A

Leerink Partners; Barclays; BMO Capital Markets

$69.6

Sancilio Pharmaceuticals Inc. (Riviera Beach, Fla.; SPCI)

8/31/15

N/A

N/A

N/A

UBS Investment Bank; Piper Jaffray; JMP Securities; FBR

$86.25

Tigenix NV (Leuven, Belgium; TIG)6

12/24/15

ADS

N/A

N/A

Canaccord Genuity; Nomura; KBC Securities; Chardan Capital Markets

N/A

Visterra Inc. (Cambridge, Mass.; VIST)

1/5/16

N/A

N/A

N/A

Leerink Partners; Stifel; Needham & Co.; Wedbush Pacgrow

$69.00

Viventia Bio Inc. (Winnipeg, Manitoba; VITA)

10/21/15

N/A

N/A

N/A

Leerink Partners; Cowen and Co.; Guggenheim Securities

$86.25

Notes

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

* Stock symbols for companies seeking to complete IPOs are proposed.

N/A = Not available, applicable or reported.

The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.

This chart includes only biotech companies that develop therapeutics.

1 Adalta plans to raise up to A$10M (US$7.55M) in an IPO on the Australian Securities Exchange.

2 Advanced Inhalation's units each consist of two ordinary shares and three warrants each to purchase one ordinary share.

3 BioLight applied to list its shares for the first time in the U.S., although it already trades on the Tel Aviv Stock Exchange under the symbol "BOLT."

4 Gan & Lee plans to raise nearly ¥1.5B (US$227B) in an IPO in China

5 Noxopharm is seeking to raise A$6M (US$4.4M) in an IPO and to list on the ASX.

6 Tigenix filed a Form F-1 for a proposed IPO of its American Depository Shares to be listed on Nasdaq. The company's ordinary shares are currently listed on Euronext Brussels.