LONDON – Cancer vaccines specialist immatics Biotechnologies GmbH released new Phase II data showing advanced colorectal cancer patients who mount an immune response to its IMA910 vaccine have significantly longer overall survival than those receiving standard of care.
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LONDON – The discovery that hepatitis C viruses (HCVs) probably use the same molecular switch to control their replication could lead to new treatments for that infection.
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Genmab A/S is getting $2 million up front and could receive up to $173 million more in milestone payments on the strength of a deal with Novartis AG on its bispecific antibody technology, DuoBody.
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LONDON – Acacia Pharma Ltd. reported positive results in a Phase II study of ADP421 in the prevention of postoperative nausea and vomiting (PONV) and is now progressing the compound to Phase III, as it mulls the commercialization strategy. Read More
Genzyme Corp.'s once-daily oral multiple sclerosis drug Aubagio (teriflunomide) hit the two main clinical endpoints in a confirmatory pivotal Phase III trial: an annualized reduction in relapse rate and a reduction in the risk of sustained accumulation of disability.
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CHICAGO – Roche AG subsidiary Genentech Inc. and partner ImmunoGen Inc. had what looks to be another winner at Sunday's plenary session of the American Society of Clinical Oncology (ASCO) annual meeting.
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• BioAlliance Pharma SA, of Paris, said the FDA accepted for review its new drug application for Sitavig (acyclovir Lauriad) for recurrent orofacial herpes. The application was based on results from a Phase III study showing that a single application of the drug, marketed in Europe as Sitavir, significantly reduced the occurrence of vesicular lesions and crusts, their time to healing and the severity of symptoms.
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